Healthcare & Biotechnology Screener

Healthcare ETFs 2026

Screen leading healthcare ETFs. Compare pharmaceutical giants, medical device pioneers, health insurers, and biotechnology innovators offering non-cyclical cash flows and demographic tailwinds.

Total Funds

Healthcare ETFs tracked

Total AUM

$123.48B

Combined assets under management

Median Yield

0.85%

Trailing 12-month median payout

Average Expense Ratio

0.50%

Lowest fee starts at 0.08% (XLV)

Healthcare ETFs Highlights & Top Assets by AUM

Largest by AUM

XLV

Health Care Select Sector SPDR Fund

AUM $47.05B

Fee 0.08%

3-Mo TR +14.1%

State Street Analyze fund

#2 by AUM

VHT

Vanguard Health Care Index Fund ETF Shares

AUM $20.01B

Fee 0.09%

3-Mo TR +12.5%

Vanguard Analyze fund

#3 by AUM

IBB

iShares Nasdaq Biotechnology ETF

AUM $11.01B

Fee 0.44%

3-Mo TR +12.1%

BlackRock, Inc. Analyze fund

Healthcare ETFs Directory

Showing 1–20 of 55 funds

Ticker / Fund Name	Issuer	Segment	AUM	Expense Ratio	3-Mo TR	Div. Yield (TTM)	Annual Payout	5Y Div Growth	Div Streak	Action
XLV XLV State Street Health Care Select Sector SPDR Fund	State Street	Stocks in healthcare (US)	$47.05B	0.08%	+14.1%	1.13%	$1.91	6.23%	5 y	Analyze
VHT Vanguard Vanguard Health Care Index Fund ETF Shares	Vanguard	Stocks in healthcare (US)	$20.01B	0.09%	+12.5%	1.46%	$4.62	11.34%	5 y	Analyze
IBB BlackRock, Inc. iShares Nasdaq Biotechnology ETF	BlackRock, Inc.	Stocks in biotechnology (US)	$11.01B	0.44%	+12.1%	0.16%	$0.33	4.54%	-	Analyze
XBI XBI State Street SPDR S&P Biotech ETF	State Street	Stocks in biotechnology (US)	$10.62B	0.35%	-0.3%	0.35%	$0.55	28.12%	2 y	Analyze
IXJ BlackRock, Inc. iShares Global Healthcare ETF	BlackRock, Inc.	Stocks in healthcare (global)	$4.49B	0.38%	+12.3%	1.41%	$1.44	10.78%	3 y	Analyze
IYH BlackRock, Inc. iShares U.S. Healthcare ETF	BlackRock, Inc.	Stocks in healthcare (US)	$4.47B	0.37%	+13.9%	0.85%	$0.61	6.19%	4 y	Analyze
FHL FHLC Fidelity Fidelity MSCI Health Care Index ETF	Fidelity	Stocks in healthcare (US)	$3.82B	0.08%	+12.5%	1.25%	$1.02	4.38%	4 y	Analyze
IHI BlackRock, Inc. iShares U.S. Medical Devices ETF	BlackRock, Inc.	Stocks in healthcare equipment (US)	$3.48B	0.37%	+11.2%	0.51%	$0.26	3.48%	-	Analyze
FBT FBT First Trust First Trust NYSE Arca Biotechnology Index Fund	First Trust	Stocks in biotechnology (US)	$3.01B	0.55%	+11.2%	0.00%	-	-	-	Analyze
ARKG ARK Invest LLC ARK Genomic Revolution ETF	ARK Invest LLC	Stocks in genomics (global)	$2.09B	0.75%	+23.2%	0.00%	-	-13.53%	-	Analyze
IHE BlackRock, Inc. iShares U.S. Pharmaceuticals ETF	BlackRock, Inc.	Stocks in pharmaceuticals (US)	$1.54B	0.37%	+4.4%	1.43%	$1.43	16.01%	2 y	Analyze
IHF IHF BlackRock, Inc. iShares U.S. Healthcare Providers ETF	BlackRock, Inc.	Stocks in healthcare providers (US)	$1.38B	0.37%	+8.0%	0.99%	$0.54	14.92%	1 y	Analyze
FXH FXH First Trust First Trust Health Care AlphaDEX® Fund	First Trust	Stocks in healthcare (US)	$1.14B	0.61%	+12.5%	0.34%	$0.44	-	3 y	Analyze
FTX FTXH First Trust First Trust Nasdaq Pharmaceuticals ETF	First Trust	Stocks in pharmaceuticals (US)	$1.14B	0.60%	+12.8%	0.70%	$0.29	16.86%	6 y	Analyze
PBP PBPH TFG Parent Holdings LLC Portfolio Building Block World Pharma and Biotech Index ETF	TFG Parent Holdings LLC	Stocks in pharma and biotech (developed markets)	$1.11B	0.13%	+12.0%	0.08%	$0.02	-	-	Analyze
PPH PPH VanEck VanEck Vectors ETF Trust - VanEck Vectors Pharmaceutical ETF	VanEck	Stocks in pharmaceuticals (global)	$1.07B	0.36%	+8.1%	1.99%	$2.17	16.82%	3 y	Analyze
RSP RSPH Invesco Invesco S&P 500® Equal Weight Health Care ETF	Invesco	Stocks in healthcare (US)	$958.24M	0.40%	+19.6%	0.46%	$0.17	11.05%	9 y	Analyze
PJP Invesco Invesco Dynamic Pharmaceuticals ETF	Invesco	Stocks in pharmaceuticals (US)	$558.37M	0.58%	+7.4%	0.92%	$1.13	12.37%	6 y	Analyze
BBH VanEck VanEck Vectors Biotech ETF	VanEck	Stocks in biotechnology (global)	$509.44M	0.35%	+23.5%	0.39%	$0.96	9.49%	-	Analyze
XPH XPH State Street SPDR Series Trust - SPDR S&P Pharmaceuticals ETF	State Street	Stocks in pharmaceuticals (US)	$447.70M	0.35%	-5.5%	0.42%	$0.28	13.67%	-	Analyze
PBE PBE Invesco Invesco Dynamic Biotechnology & Genome ETF	Invesco	Stocks in biotechnology (US)	$431.71M	0.59%	+11.3%	1.37%	$1.33	-	3 y	Analyze
IDN IDNA BlackRock, Inc. iShares Genomics Immunology and Healthcare ETF	BlackRock, Inc.	Stocks in genomics (global)	$331.83M	0.47%	+26.7%	0.66%	$0.28	-	1 y	Analyze
PIN PINK Simplify Simplify Exchange Traded Funds - Simplify Health Care ETF	Simplify	Stocks in healthcare (US)	$324.39M	0.51%	+4.5%	0.52%	$0.20	-	1 y	Analyze
PTH PTH Invesco Invesco DWA Healthcare Momentum ETF	Invesco	Stocks in healthcare (US)	$290.31M	0.60%	-1.0%	0.00%	-	-	1 y	Analyze
XHS XHS State Street SPDR® S&P Health Care Services ETF	State Street	Stocks in healthcare providers (US)	$220.56M	0.35%	+7.3%	0.15%	$0.20	5.30%	-	Analyze
CAN CANC Dawn Global Topco Ltd. Tema Oncology ETF	Dawn Global Topco Ltd.	Stocks in pharma and biotech (global)	$211.78M	0.75%	+1.1%	0.05%	$0.02	-	-	Analyze
SBI SBIO SS&C Technologies Holdings, Inc. ALPS ETF Trust - ALPS Medical Breakthroughs ETF	SS&C Technologies Holdings, Inc.	Stocks in biotechnology (US)	$188.44M	0.50%	-14.9%	0.00%	-	-	-	Analyze
PSC PSCH Invesco Invesco S&P SmallCap Health Care ETF	Invesco	Stocks in healthcare (US)	$170.32M	0.29%	+2.6%	0.00%	-	-	-	Analyze
XHE XHE State Street SPDR Series Trust - SPDR S&P Health Care Equipment ETF	State Street	Stocks in medical equipment (US)	$148.53M	0.35%	+9.6%	0.00%	-	-	2 y	Analyze
BBP BBP Virtus Investment Partners Virtus LifeSci Biotech Products ETF	Virtus Investment Partners	Stocks in biotechnology (US)	$131.11M	0.34%	+7.2%	0.00%	-	-	-	Analyze
LFS LFSC F/m Investments LLC F/m Emerald Life Sciences Innovation ETF	F/m Investments LLC	Stocks in pharma and biotech (US)	$122.49M	0.54%	-5.4%	0.00%	-	-	-	Analyze
IBB IBBQ Invesco Invesco Nasdaq Biotechnology ETF	Invesco	Stocks in pharma and biotech (US)	$114.79M	0.19%	+9.2%	1.11%	$0.39	26.91%	5 y	Analyze
KUR KURE CICC KraneShares MSCI All China Health Care Index ETF	CICC	Stocks in healthcare (China)	$112.19M	0.65%	-0.7%	3.71%	$0.71	478.87%	3 y	Analyze
HTE HTEC Exchange Traded Concepts Robo Global® Healthcare Technology and Innovation ETF	Exchange Traded Concepts	Stocks in healthcare technology (global)	$111.11M	0.68%	+19.4%	0.78%	$0.35	-	-	Analyze
GNO GNOM Mirae Asset Global Investments Co., Ltd. Global X Genomics & Biotechnology ETF	Mirae Asset Global Investments Co., Ltd.	Stocks in genomics (global)	$110.19M	0.50%	+20.7%	0.92%	$0.65	90.27%	1 y	Analyze
OZE OZEM Roundhill Investments Roundhill GLP-1 & Weight Loss ETF	Roundhill Investments	Stocks in pharma and biotech (global)	$56.12M	0.59%	-7.0%	1.33%	$0.41	-	1 y	Analyze
HRT HRTS Dawn Global Topco Ltd. Tema Cardiovascular and Metabolic ETF	Dawn Global Topco Ltd.	Stocks in pharma and biotech (global)	$55.53M	0.75%	+5.1%	1.30%	$0.47	-	1 y	Analyze
FME FMED Fidelity Fidelity Disruptive Medicine ETF	Fidelity	Stocks in healthcare (global)	$52.07M	0.50%	+11.7%	0.00%	-	-	-	Analyze
PSI PSIL AdvisorShares AdvisorShares Psychedelics ETF	AdvisorShares	Stocks in pharma and biotech (global)	$45.22M	1.00%	-13.4%	0.00%	-	-	2 y	Analyze
MED MEDI ORIX Harbor Health Care ETF	ORIX	Stocks in healthcare (global)	$42.75M	0.80%	+3.4%	0.23%	$0.07	-	-	Analyze
BBC BBC Virtus Investment Partners Virtus LifeSci Biotech Clinical Trials ETF	Virtus Investment Partners	Stocks in life-science tools (US)	$40.28M	0.65%	-16.8%	1.41%	$0.66	-	2 y	Analyze
EDO EDOC Mirae Asset Global Investments Co., Ltd. Global X Telemedicine & Digital Health ETF	Mirae Asset Global Investments Co., Ltd.	Stocks in healthcare equipment and services (global)	$34.93M	0.68%	-5.0%	0.00%	-	-	1 y	Analyze
HEL HELX Franklin Templeton Franklin Genomic Advancements ETF	Franklin Templeton	Stocks in genomics (global)	$34.70M	0.50%	+10.2%	0.32%	$0.14	22.42%	-	Analyze
TME TMED T. Rowe Price Group, Inc. T. Rowe Price Health Care ETF	T. Rowe Price Group, Inc.	Stocks in healthcare (global)	$34.22M	0.44%	+2.0%	0.48%	$0.16	-	-	Analyze
XLV XLVI State Street State Street® Health Care Select Sector SPDR® Premium Income ETF	State Street	Stocks in healthcare (US)	$32.74M	0.35%	+7.7%	12.39%	$3.27	-	1 y	Analyze
HEA HEAL Mirae Asset Global Investments Co., Ltd. Global X HealthTech ETF	Mirae Asset Global Investments Co., Ltd.	Stocks in healthcare (global)	$32.16M	0.50%	+16.2%	0.49%	$0.14	-	1 y	Analyze
GDO GDOC Goldman Sachs Goldman Sachs ETF Trust	Goldman Sachs	Stocks in healthcare technology (global)	$19.80M	0.75%	+7.2%	0.30%	$0.11	-	1 y	Analyze
MED MEDX Horizon Kinetics Holding Corp. Horizon Kinetics Medical ETF	Horizon Kinetics Holding Corp.	Stocks in healthcare (global)	$17.15M	0.85%	+6.0%	1.16%	$0.41	-	-	Analyze
BME BMED BlackRock, Inc. BlackRock Future Health ETF	BlackRock, Inc.	Stocks in healthcare (global)	$14.25M	0.55%	+16.9%	0.47%	$0.16	-	-	Analyze
EKG EKG First Trust First Trust Nasdaq Lux Digital Health Solutions ETF	First Trust	Stocks in healthcare equipment and services (global)	$9.61M	0.65%	+27.9%	0.00%	-	-	-	Analyze
JDO JDOC JPMorgan Chase JPMorgan Healthcare Leaders ETF	JPMorgan Chase	Stocks in healthcare (global)	$9.50M	0.65%	+7.1%	0.85%	$0.51	-	-	Analyze
FDH FDHT Fidelity Fidelity Covington Trust - Fidelity Digital Health ETF	Fidelity	Stocks in healthcare equipment and services (global)	$8.13M	0.39%	+0.1%	0.00%	-	-	2 y	Analyze
CNC CNCR Exchange Traded Concepts Loncar Cancer Immunotherapy ETF	Exchange Traded Concepts	Stocks in pharma and biotech (global)	$6.94M	0.79%	-27.5%	0.00%	-	45.10%	-	Analyze
IBR IBRN BlackRock, Inc. iShares Trust - iShares Neuroscience and Healthcare ETF	BlackRock, Inc.	Stocks in pharma and biotech (global)	$6.30M	0.47%	-15.4%	0.96%	$0.32	-	2 y	Analyze
THN THNR Amplify Investments Amplify ETF Trust	Amplify Investments	Stocks in pharma and biotech (developed markets)	$5.73M	0.59%	-2.7%	1.64%	$0.41	-	1 y	Analyze

Data as of November 2026. Ranked by AUM. This list was compiled by the Snowball Analytics team from publicly available sources. It may be incomplete, and figures may be delayed or contain errors; check them against the fund’s or company’s own documents. Inclusion in the list is not a recommendation to buy, sell or hold any security and is not investment advice. Past performance does not predict future results. This list is general information, not personalised to your circumstances. Snowball Analytics is a portfolio tracking tool, not a broker-dealer or investment adviser. Investing involves risk, including loss of principal.

Understanding Healthcare ETFs: Pharmaceuticals, Biotech & Medical Devices

Healthcare ETFs invest in companies operating across pharmaceuticals, medical technology, health insurance, and hospital administration. The sector combines defensive, non-cyclical consumer demand with demographic growth from aging global populations.

Core Strategies & Segment Breakdowns

Broad Healthcare Giants

Flagships like XLV and VHT holding blue-chip market leaders (Eli Lilly, UnitedHealth, Johnson & Johnson) with steady cash flows.

Biotechnology & Drug Discovery

High-growth baskets like IBB and XBI targeting clinical research, gene editing, and novel therapeutic development.

Medical Devices & Diagnostics

Focusing on precision surgical robotics, cardiovascular equipment, and diagnostic testing equipment manufacturers.

How to Evaluate Healthcare ETFs (Investor Checklist)

Distinguish Big Pharma from Early-Stage Biotech: Large pharmaceuticals offer stable dividends and high cash flow, whereas equal-weighted biotech funds face binary drug approval outcomes.
Evaluate Regulatory and Patent Cliff Risks: Monitor government drug price negotiation policies and patent expiration dates on blockbuster treatments.
Check Sub-Sector Allocation: Confirm whether the fund tilts toward defensive managed care or high-beta medical device innovators.

Frequently Asked Questions About Healthcare ETFs

Why is healthcare considered a defensive investment sector?

Demand for prescription medications, emergency medical treatment, and health insurance remains stable regardless of economic slowdowns or recessions.

How does XLV differ from biotech-focused funds like XBI?

XLV holds large-cap, highly profitable pharmaceutical and health insurance conglomerates, while XBI equal-weights smaller, clinical-stage biotechnology firms.

Which Healthcare ETFs currently have the highest AUM?

In this category, Health Care Select Sector SPDR Fund (XLV) leads with over $47.05B in Assets Under Management, offered by State Street.

Which healthcare ETF has the largest asset base?

The Health Care Select Sector SPDR Fund (XLV) is the largest healthcare ETF, managing tens of billions with an ultra-low expense ratio.

How can I track my Healthcare ETFs with Snowball Analytics?

Snowball Analytics connects directly to your brokerage accounts to automatically track dividend payouts, calculate time-weighted and money-weighted returns (TWR and IRR) against benchmarks, model sector weighting, and monitor risk metrics across all your Healthcare ETFs holdings in one unified portfolio dashboard.

Explore More ETF Topics & Categories

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Income

ESG ETFs

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ESG

Growth ETFs

Tech & capital appreciation

Growth

Value ETFs

Deep value & fundamental multiples

Value

Low Volatility ETFs

Factor tilt & risk mitigation

Factor

Asset Allocation ETFs

All-in-one multi-asset target risk

Balanced

Silver ETFs

Physically vaulted silver bullion

Metals

Palladium ETFs

Automotive catalysts & platinum group

Metals

Silver Miners ETFs

Operating leverage to silver prices

Miners

Timber & Forestry ETFs

Timberland REITs & paper packaging

Timber

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