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 Outstanding nominal value as of the current date

Average price of a bond, in % of face value

The current yield indicates the ratio of the accrued coupon to the current market price of the bond. It can be used in cases where attachments are considered for a short period of time. In this situation, the change in the market price can sometimes be neglected.

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Effective yield to maturity. It considers both coupon income and profit/loss due to the difference between the purchase price and the repayment price. Effective yield shows the investor the return on invested funds with reinvested coupons and depreciation.

Listing level — stock exchange assessment of securities reliability.

The ratio of the annual coupon to the "dirty" price of the bond, including the accrued interest. This type of yield can be used in the case of short-term investments, when the investment horizon is within one coupon period.

Average purchase price of a bond, in % of face value

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Coupon yield % per annum of nominal value (coupon amount per year/nominal value)

 Simple yield to maturity. It considers both coupon income and profit/loss due to the difference between the purchase price and the repayment price. Simple yield shows the investor the return on invested funds without reinvested coupons.

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The fund expense ratio is the annual fee expressed as a percentage of a mutual fund or ETF's average assets, covering management, administrative, and other operational costs. It directly reduces investors' returns.

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Qyuns Therapeutics Co., Ltd., a clinical-stage biotech company, engages in the research and development of biologic therapies for autoimmune and allergic diseases in the People's Republic of China. Its lead product candidates include QX002N, an interleukin (IL)-17A inhibitor, which is in Phase III clinical trial for the treatment of ankylosing spondylitis; and QX005N, a monoclonal antibody (mAb) blocking IL-4Ra that is in Phase III clinical trial for treating prurigo nodularis. The company also develops QX001S, which is an IL-12/L-23p49 inhibitor for psoriasis under the SAILEXIN brand. In addition, the company develops QX008N, a humanized IgG1 mAb targeting thymic stromal lymphopoietin that is in Phase Ib clinical trial to treat moderate-to-severe asthma and chronic obstructive pulmonary disease (COPD); QX004N, an IL-23p19 inhibitor, which is in Phase II clinical trial to treat psoriasis and Crohn's disease; QX013N, a humanized IgG1 mAb targeting c-kit; QX006N, an IFNAR1-targeting mAb that is in Phase Ib clinical trial for the treatment of systemic lupus erythematosus; QX007N, a humanized IgG1 mAb targeting IL-33 for treating moderate-to-severe COPD and asthma; and QX010N, an IL-31R inhibitor for the treatment of pruritus. Further, it manufactures and sells pharmaceutical products; and provides technical consultation services. The company was incorporated in 2015 and is headquartered in Taizhou, China.

Qyuns Therapeutics Co Ltd

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