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Lexeo Therapeutics, Inc., a clinical stage genetic medicine company, focuses on hereditary and acquired diseases with high unmet need in the United States. Its product pipeline comprises LX2006, an AAVrh10-based gene therapy candidate, which is in phase 1/2 clinical trial to treat friedreich ataxia cardiomyopathy; LX2020, an AAVrh10-based gene therapy candidate, which is in phase 1/2 to deliver a functional plakophilin-2 (PKP2) gene to cardiac muscle for the treatment of PKP2-ACM; and LX2021, a gene therapy candidate, which is in preclinical trial to deliver the coding sequence for the functional connexin 43, or Cx43, protein for a group of inherited cardiac muscle disorders associated with a high risk of sudden death, including arrhythmogenic cardiomyopathy (ACM) and certain forms of dilated cardiomyopathy. The company is also developing LX2022, a gene therapy candidate, which is in preclinical trial to deliver a functional TNNI3 gene to myocardial cells to treat a distinct form of hypertrophic cardiomyopathy. In addition, it is developing LX1001, LX1020, and LX1021, an AAVrh10-based gene therapy candidate, which has completed phase 1/2 clinical trial for the treatment of APOE4-associated Alzheimer's disease. The company has a license agreement with Cornell University to conduct the Phase 1/2 clinical trial of LX1001, as well as support the development of the LX1004 program; a research collaboration agreement with Cornell University to conduct preclinical research to develop the licensed technology; and third license agreement which obtained certain rights for FA cardiomyopathy, including rights to current and future clinical data from an ongoing Cornell University investigator-initiated Phase 1A trial of a gene therapy candidate. The company was founded in 2017 and is headquartered in New York, New York.

	2021	2022	2023	2024	2025	TTM
Revenue
Total revenue	1.657	0.654	-	-	-	-
COGS	0.0134	1.145	1.843	2.001999	2.079	-
Gross Profit	1.657	0.654	(1.843)	(2.001999)	(2.079)	-
Operating Expenses & Income
Operating Income	(50.64)	(60.51)	(68.51)	(105.8)	(109.3)	(95.12)
Total Operating Expenses	52.29	61.16	68.51	105.8	109.3	94.57
R&D Expenses	45.12	49.16	53.13	74.09	63.8	66.64
Selling General & Admin Expenses	7.173	12	15.38	31.68	45.46	28.48
Earnings from Continuing Operations
Interest Expense	-	(0.091)	(0.205)	(0.114)	(0.206)	(0.138)
Interest Income	0.015	1.325	2.867	7.579	6.13	5.824
Income Tax Expense	(0.000155)	0.089	(0.000001)	-	-	-
Net Income
Net Income	(50.62)	(59.28)	(66.39)	(98.33)	(99.96)	(87.27)
Supplemental
EBIT	(50.62)	(59.19)	(66.19)	(98.2)	(99.75)	(87.13)
EBITDA	(50.61)	(58.04)	(64.35)	(96.19)	(97.68)	(85.44)

Lexeo Therapeutics Inc. Common Stock